Cuenca del Lago de Yojoa includes the only lake of volcanic origin in Honduras. In 2021 Honduras extended the Site's area from 43,640 to 44,253.94 ha. It is formed by 16 ecosystems serving as a refuge for a wide diversity of aquatic and terrestrial species including 55% of birds, 44.2% of amphibians, and 43.6% of the reptiles present in the country. The Site, a river basin protected by law, provides shelter and habitat for species included in the IUCN Red List such as the critically endangered salamander Dendrotriton sanctibarbarus and the Guatemala spikethumb frog (Plectrohyla guatemalensis). There are also vulnerable species such as the Geoffroy’s spider monkey (Ateles geoffroyi) and the Honduran emerald (Amazilia luciae), an endemic hummingbird. The main threats are deforestation, extensive farming, the advance of the agricultural frontier, and the introduction of exotic species.